Narcolepsy is a severe chronic neurologic disease that not only results in a disabling fatigue, which typically results in the patient falling asleep anywhere and at any time. If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Squalene medicine then it may not be safe to drive a vehicle or operate heavy machinery.One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. (India). On 25 September 2009, the European Medicines Agency (EMEA) approved Pandemrix, the swine flu vaccine produced by GSK and Focetria produced by Novartis. Mass vaccination started in Finland and Sweden in October 2009. Although squalene is a natural substance found in methabolic pathways of the body, its inclusion in a vaccine is controversial and it is not in use in the USA. http://justthevax.blogspot.com/2009/09/eu-approves-gsk-pandemrix-and-novartis.html The vaccine would be ready for use that October. Martin P. Gallagher, M.D., D.C. (USA) On 1 September 2010, Finland stopped all Pandemrix vaccinations. (i[r].q=i[r].q||[]).push(arguments)},i[r].l=1*new Date();a=s.createElement(o), Erik Paterson, M.D. Referring to squalene in her extensive article on adjuvants, Dr. Scheibner writes, “This adjuvant contributed to the cascade of reactions called “Gulf War syndrome”, documented in the soldiers involved in the Gulf War. The European Center for Disease Prevention and Control (ECDC) stated that the swine flu was less dangerous and had a lower mortality rate than the seasonal influenza. They describe some of the affected children narrating how difficult it is to live with narcolepsy http://www.svd.se/nyheter/multimedia/artikel_6840743.svd. Squalene's chemical similarity to human skin sebum has made it a popular component in natural cosmetic formulas designed to soften and protect the skin. … Squalene has historically been sourced from shark liver oil, although more recently other plant and vegetable sources have been identified. In contrast, the figures in Germany and Poland were only 8 and 0% respectively. http://articles.mercola.com/sites/articles/archive/2010/09/10/swine-flu-vaccine-may-have-caused-narcolepsy.aspx. Total cholesterol concentrations increased by 32% in the 0.05% squalene group, 23% in the 0.1% squalene group, 35% in the 0.5% squalene group, and 19% in the … To Subscribe at no charge: http://www.orthomolecular.org/subscribe.html, To Unsubscribe from this list: http://www.orthomolecular.org/unsubscribe.html. 1. The medication has minimal side effects and is basically harmless. A 47-year-old member asked: what are the side effects of using sunscreen on your face everyday? The responsible authorities have not yet commented on this matter of fact. By using our website, you consent to our use of cookies. In mice with intestinal tumors, a combination of squalene-cisplatin prevented the formation of tumors without any signs of toxic side effects . Carolyn Dean, M.D., N.D. (USA) Squalene is a natural substance most commonly known as fish oil and shark liver oil when put in supplement form. This website is managed by Riordan Clinic Dean Elledge, D.D.S., M.S. Orthomolecular Medicine News Service, March 20, 2012. Squalene is an ansaturated oil that occurs naturally in a lot of different species of plants and animals, and it also occurs naturally in our own skin. This was 12.7 times the risk of a person in the same age group who had not been vaccinated." Squalene effects on cholesterol were assessed in hamsters given diets with 0.05%, 0.1%, or 0.5% squalene or 0.05% squalene-containing SLO for 4 weeks. http://www.thl.fi/en_US/web/en/pressrelease?id=26352 This statement was made almost exactly two years after the THL's earlier statement made in the midst of the swine flu hysteria that everyone should be vaccinated with Pandemrix and that it would be safe. (USA) On 1 September 2011, the Finnish National Institute for Health and Welfare (THL) admitted, that for Finnish children and youngsters age 4-19, there was a new and obvious connection between Pandemrix and narcolepsy. ga('create', 'UA-16632634-4', 'auto'); Squalene is sometimes used as an adjuvant in vaccines — that is, an agent that stimulates the immune system and increases the response to a vaccine. HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes. If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Squalene Topical medicine then it may not be safe to drive a vehicle or operate heavy machinery.One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. The lab-made version of squalamine is sometimes applied directly to the skin as an antibiotic.. Thus, apparently the swine flu would not have been a dangerous epidemic even without the mass vaccination. The symptoms they developed included arthritis, fibromyalgia, … http://www.svd.se/nyheter/inrikes/medicinsk-tragedi-med-ett-absurt-slut_6861775.svd, No European countries had a particularly high rate of deaths due to the swine flue. In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. On 25 September 2009, the European Medicines Agency (EMEA) approved Pandemrix, the swine flu vaccine produced by GSK and Focetria produced by Novartis. Robert E. Jenkins, D.C. (USA) Tell your doctor if you have side effects that you think are caused by this medicine. No evidence that it works and only several small studies on it. In a study published in the International Journal of Cancer in July 2006, s… (Australia) http://www.svd.se/nyheter/inrikes/svd-granskar-sveriges-vaccinering-mot-svininfluensan_6843475.svd. Squalene, a hydrocarbon obtained for commercial purposes primarily from shark liver oil and other botanic sources, is increasingly used as an immunologic adjuvant in several vaccines, including seasonal and the novel influenza A (H1N1) 2009 pandemic flu vaccines. Squalene is effective in the treatment of diabetes mellitus type 2 and can potentiate the activity of some antitumor (antiblastoma) preparations and reduce their undesired side effects. (Puerto Rico) For more information: http://www.orthomolecular.org, To locate an orthomolecular physician near you: http://orthomolecular.org/resources/omns/v06n09.shtml. Information on Orthomolecular.org is provided for educational purposes only. In February 2012, Svenska Dagbladet, a widely read newspaper in Sweden, presented an informative and accurate series of articles on this theme. Michael Ellis, M.D. Email: omns@orthomolecular.org Readers may write in with their comments and questions for consideration for publication and as topic suggestions. (USA) In 2009 vaccines were being developed for the prevention of swine flu in humans. Squalene is not licensed for use on either side of the Atlantic because of potential side effects. This virus was originally referred to as "swine flu" because many of the genes of this new virus were very similar to influenza viruses that normally occur in pigs in North America. SIDE EFFECTS. [4] Let's hope so. Squalene was first isolated from shark liver, but was later found to be ubiquitously distributed. More common side effects of this antibiotics are nausea and vomiting , the skin reaction with intolerance. Squalane vs. Squalene. This condition causes the narcolepsy patient, when expressing strong feelings such as laughter or crying, to suddenly lose muscular control. The hydrogenation process makes squalane more shelf-stable than squalene and, therefore, easier to use in skin-care products. 3100 North Hillside Avenue, Wichita, KS 67219 USA http://www.svd.se/nyheter/inrikes/massvaccinering-raddade-sex-liv_6851143.svd. This virus first caused illness in Mexico and the United States in March and April, 2009. Orthomolecular medicine uses safe, effective nutritional therapy to fight illness. Meanwhile, the media had become silent on this issue ; there was no further discussion about the swine flu anymore. Consult your orthomolecular health care professional for individual guidance on specific health problems. In Sweden, Finland, Norway and Iceland, the authorities explicitly set the goal of vaccinating the entire population http://www.svd.se/nyheter/inrikes/massvaccinering-raddade-sex-liv_6851143.svd. })(window,document,'script','https://www.google-analytics.com/analytics.js','ga'); })(window,document,'script','https://www.google-analytics.com/analytics.js','ga'); Extensive research done on other squalene-containing vaccines used around the world links Squalene to long-term severe neurological and immune system dysfunction. Different pills/meds have different effects as well side effects. In order to cover the largest possible percentage of the population, the authorities initiated an enormous public relations campaign, which could be described in terms of a "moral persuasion." ga('create', 'UA-16632634-4', 'auto'); http://www.svd.se/nyheter/inrikes/svd-granskar-sveriges-vaccinering-mot-svininfluensan_6843475.svd, The expected second wave of the influenza never appeared. Squalene is effective in the treatment of diabetes mellitus type 2 and can potentiate the activity of some antitumor (antiblastoma) preparations and reduce their undesired side effects. Squalene. Unless you consider the negatives associated with excessive self-indulgence. In some patients, frightening hallucinations appear when falling asleep or waking up. [2] Like cholesterol, it is secreted through the skin[3] and is important in the Skin Surface Lipid (SSL) film that protects the body from the external environment. Andrew W. Saul, Ph.D. (USA), Editor and contact person. 36 years experience Breast Surgery. it has been 6 weeks now. Squalene is a Triterpenoid compound[1] that is synthesized in vivo by human livers as a precursor to cholesterol synthesis. Those who questioned the vaccination program (small groups of vaccine opponents or just people who were hesitant) were looked upon with disapproval. (United Kingdom) Ralph K. Campbell, M.D. When WHO declared the swine flu to be a Phase 6 pandemic, the agreement referred to above was automatically activated. squalene side effects A 55-year-old male asked: i was prescribed doxycycline 100 mg/day for 3 months for scalp foliculitis that disappeared after about 2.5 weeks. To learn more, please visit our. Squalane is a botanical lipid, with a similar structure to squalene but it is mainly derived from the olive fruit tree (amongst other sources). In a pharmaceutical application, squalene has been used as adjuvant in many vaccines and controversies arose during the 1991 Gulf War concerning its possible side effects, when injected. Robert G. Smith, Ph.D. (USA) (Canada) This novel H1N1 flu spread from person to person, unlike typical swine flu. Side Effects & Safety Squalamine is POSSIBLY SAFE in adults when used as eye drops for up to 38 weeks or when injected in the vein by a health care professional. However, this new virus was actually quite different from the typical swine flu viruses. It is not intended as medical advice. (function(i,s,o,g,r,a,m){i['GoogleAnalyticsObject']=r;i[r]=i[r]||function(){ Immunologic adjuvants are substances, administered in conjunction with a vaccine, that stimulate the immune system and increase the response to the vaccine http://www.who.int/vaccine_safety/topics/adjuvants/squalene/questions_and_answers/en/. Denmark's order covered only "risk groups". In mice, squalene reduced the DNA damage caused by the chemotherapy drug doxorubicin, especially when squalene … Two pharmaceutical companies GlaxoSmithKline (GSK) and Novartis had, under considerable time pressure, developed a vaccine against the swine flu. This bioactive substance has low toxicity and, in therapeutic doses, does not produce any damaging action on the human organism. The epidemic gradually declined during the first half of 2010. (i[r].q=i[r].q||[]).push(arguments)},i[r].l=1*new Date();a=s.createElement(o), Other Side Effects: You may have the following side effects, but this medicine may also cause other side effects. Long List of Side Effects. Since the cultivation of an adequate amount of virus to generate the vaccine requires time, GSK and Novartis decided to formulate a weaker vaccine but strenghten it with an adjuvant that contains squalene. W. Todd Penberthy, Ph.D. (USA) Consult your orthomolecular health care professional for individual guidance on specific health problems. In addition, the contract stipulated that, in a situation characterized as a pandemic by the WHO, the same Nordic countries would have ten days to decide whether or not to accept delivery of the vaccine in question. In the history of Swedish health care this pandemic campaign amounted to one of the most expensive ever. Grant, Ph.D. (USA) m=s.getElementsByTagName(o)[0];a.async=1;a.src=g;m.parentNode.insertBefore(a,m) Pneumonia (lung problem) has occurred when taking Squalene as shark oil (2) Michael Janson, M.D. Long-term side effects for military veterans who received the anthrax vaccine with the Squalene adjuvant may include: Autoimmune arthritis; … The most common ( ≥ 10%) local (injection-site) adverse reactions observed in clinical studies were tenderness, pain, erythema, edema, and arm motion limitation.The most common ( ≥ 5%) systemic adverse reactions were muscle aches, headache, and fatigue. Many have already began to compare this tragedy with the thalidomide catastrophe. The H1N1 virus is genetically similar to the 1918 pandemic virus, as determined from victimes of the latter who were buried, and later disinterred, in Svalbard. William B. The desired immune response to vaccines is the production of antibodies, and this is enhanced by adding certain substances to the vaccines. A Non-profit 501(c)(3) Medical, Research and Educational Organization Squalene is the precursor of cholesterol. Jagan Nathan Vamanan, M.D. I would not want someone i cared for s ... i was prescribed doxycycline 100 mg/day for 3 months for scalp foliculitis that disappeared after about 2.5 weeks. In both countries the number is probably growing. Oxidative stress often occurs when the skin is exposed to sunlight and other forms of environmental stress. ga('send', 'pageview'); Information on Orthomolecular.org is provided for educational purposes only. Top answers from doctors based on your search: Connect by text or video with a U.S. board-certified doctor now — wait time is less than 1 minute! Research has linked a Mediterranean diet high in … it has been 6 weeks now. can i start taking doxycycline every other day now. Squalene consumption may also reduce the risk of heart attacks, irregular heart rhythms, and high blood pressure. ADJUVANTS. The majority of symptomatic GWS patients had serum antibodies to squalene.” According to Dr. Viera Scheibner, Ph.D., a former principal research scientist for the government of Australia: “ … this adjuvant [squalene] contributed to the cascade of reactions called “Gulf War Syndrome,” documented in the soldiers … In this article, the first of a two-part series, we shall deal with adjuvants, their expects role and the reactions (side effects). "The worst nightmare of both the industry and the health authorities is an illness that turns out to be mild, while the vaccine that was supposed to prevent a dangerous epidemic causes a severe side effect that was previously unknown." Jorge R. Miranda-Massari, Pharm.D. The peer-reviewed Orthomolecular Medicine News Service is a non-profit and non-commercial informational resource. http://www.who.int/mediacentre/news/statements/2009/h1n1_pandemic_phase6_20090611/en/index.html. Although squalene is a natural substance found in methabolic pathways of the body, its inclusion in a vaccine is controversial and it is not in use in the USA. http://www.kostdemokrati.se/nyheter/files/2012/02/SvD-sid-14-19.pdf, In August 2010, Finland reported an increased occurrence of narcolepsy in children and youngsters vaccinated with Pandemrix. i am concerned about side effects. In this portion of HealthTap we provide health education but we can't provide tr ... A question. (USA) Gert E. Schuitemaker, Ph.D. (Netherlands) As stated in THL's press release, "The increased risk associated with vaccination amounted to six cases of narcolepsy per 100,000 persons vaccinated in the 4-19 age group during the eight months following vaccination. Some … By folding this compound in certain modes one can construct the basic triterpenoid skeletons with angular methyl groups and side chain in correct positions. Hence, the purpose of the agreement was to assure that the entire populations of these countries would receive vaccinations. In contrast to these vaccine - enthusiastic countries, the politics of vaccination within the rest of the European Union varied immensely among its member states. However, he stated, these side effects would not be dangerous. Interestingly, also that same year, vitamin D was shown to prevent influenza in children. The antioxidant properties of squalene have also been touted as being very beneficial for many skin conditions. It might also lead to panic attacks and a state of exhaustion. What Is Squalane? can i start taking doxycycline every other day now. (Finland) 2010 May;91(5):1255-60. Germany had the same death rate as Sweden, which was 0.31/100 000, although Sweden vaccinated 60% and Germany only 8%. Squalamine is a chemical produced from the stomach and the liver of the spiny dogfish shark. Poland, for example, decided not to buy vaccines at all due to the strict agreement conditions required by the pharmaceutical companies. Antioxidants may help fight aging by protecting the skin from UV rays and free radicals, which damage skin cells and damage the … In that original statement, the director of the THL emphasized that the squalene adjuvant could increase the side effects of the vaccine to some extent. (OMNS, March 20, 2012) The swine flu pandemic of 2009 was caused by a type A influenza (H1N1) virus. (Australia) Urashima M, Segawa T, Okazaki M, Kurihara M, Wada Y, Ida H. Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren. Squalamine can also be made in the laboratory.. People take squalamine as an antibiotic to fight bacterial infections.. However, many people don't realize this substance is actually in our bloodstream, originating in the liver. In this respect, it is of interest that the governments of these countries, already before the outbreak of the swine flu, had concluded an agreement with GSK, according to which they were assured the delivery of pandemic vaccines, if needed. Margaret Chan, the Director-General of WHO, commented on the situation in a somewhat ambiguous way. Squalane is a saturated lipid that is produced when squalene is hydrogenated – in other words, combined with hydrogen. (USA) In general, garlic is one of the healthiest foods we can eat & is generally well-tolerated, but not everyone tolerates it well. It is a "supposed to decrease brain fog" herb. In Finland, the number is approximately 100. Narcolepsy is a disease with lifetime consequences, and the risk that Pandremix may have caused other neurological illnesses has not yet been excluded. … Dr. Todd Sisto answered. This implies that the vaccine did little to prevent deaths. This means that squalene counters some of the effects of oxidative stress on the skin. i am concerned about side effects. m=s.getElementsByTagName(o)[0];a.async=1;a.src=g;m.parentNode.insertBefore(a,m) Damien Downing, M.D. Thomas Levy, M.D., J.D. (USA) Stuart Lindsey, Pharm.D. While Sweden did, indeed, follow the Finnish THL in admitting the connection between the vaccine and the disease, the Swedish authorities have not yet decided whether and how to provide appropriate compensation. The legs give way, speech gets slurred, the gaze goes unfocused and the person gives the impression of being drunk. Karin Munsterhjelm-Ahumada, M.D. This is something that must be discussed with the prescribing doctor. Squalene is a popular over-the-counter Asian folk remedy derived from shark liver oil. Steve Hickey, Ph.D. (United Kingdom) http://www.bloomberg.com/news/2011-10-05/finnish-government-to-compensate-pandemrix-narcolepsy-victims.html. Squalene may reduce the severity of the side effects of chemotherapy. Michael Gonzalez, D.Sc., Ph.D. (Puerto Rico) While stressing that the swine flu had reached a serious pandemic level, she declared later in the same statement that the illness seemed to be mild and that most of the patients would recover without medical intervention. Taking the pressure from the public and the affected families into account, it will be difficult for them to avoid carrying out a thorough investigation. Last year the Finnish government promised full compensation for those who have developed narcolepsy as a consequence of the vaccination. (function(i,s,o,g,r,a,m){i['GoogleAnalyticsObject']=r;i[r]=i[r]||function(){ Bo H. Jonsson, M.D., Ph.D. (Sweden) It is not intended as medical advice. Cisplatin is a chemotherapy drug that often causes side effects. It famously causes bad ... After researching this, it appears that Lactare is an Ayurvedic medication that is sold in India. The world chose to listen to the first part of her message. FOR IMMEDIATE RELEASE Phone: 316-682-3100; Fax: 316-682-5054 Solidarity became the slogan: "Be vaccinated to protect your fellow citizens." Ian Brighthope, M.D. Although such adjuvant was approved in many countries, the US FDA has long forbidden its use. Side effects of squalene used on the face. side effects of squalene used on the face. Like many terpene compounds, squalene is fat-soluble. Nearly a decade ago, squalene was su … It was responsible for most of the outbreaks up until 1956 and then disappeared. (1), In Sweden, 60% of the population had been vaccinated, while in Finland 50% was covered. Am J Clin Nutr. Enormous amounts of taxpayer money were at stake. ga('send', 'pageview'); http://orthomolecular.org/resources/omns/index.shtml, http://www.medterms.com/script/main/art.asp?articlekey=99584, http://www.who.int/mediacentre/news/statements/2009/h1n1_pandemic_phase6_20090611/en/index.html, http://www.who.int/vaccine_safety/topics/adjuvants/squalene/questions_and_answers/en/, http://justthevax.blogspot.com/2009/09/eu-approves-gsk-pandemrix-and-novartis.html, http://www.svd.se/nyheter/inrikes/massvaccinering-raddade-sex-liv_6851143.svd, http://www.svd.se/nyheter/inrikes/svd-granskar-sveriges-vaccinering-mot-svininfluensan_6843475.svd, http://www.kostdemokrati.se/nyheter/files/2012/02/SvD-sid-14-19.pdf, http://articles.mercola.com/sites/articles/archive/2010/09/10/swine-flu-vaccine-may-have-caused-narcolepsy.aspx, http://www.thl.fi/en_US/web/en/pressrelease?id=26352, http://www.tohtori.fi/?page=5833192&id=0169960, http://www.svd.se/nyheter/inrikes/medicinsk-tragedi-med-ett-absurt-slut_6861775.svd, http://www.bloomberg.com/news/2011-10-05/finnish-government-to-compensate-pandemrix-narcolepsy-victims.html, http://www.svd.se/nyheter/multimedia/artikel_6840743.svd, http://orthomolecular.org/resources/omns/v06n09.shtml, http://www.orthomolecular.org/subscribe.html, http://www.orthomolecular.org/unsubscribe.html. Depends on formulati: Some have been minimally accused of being carcinogenic but the cancer risk in not using it is … The same year, on 10 August, WHO officially declared the end of the epidemic. James A. Jackson, Ph.D. (USA) This bioactive substance has low toxicity and, in therapeutic doses, does not produce any damaging action on the human organism. http://www.tohtori.fi/?page=5833192&id=0169960, In Sweden, at least 150 children are now suffering from narcolepsy caused by Pandemrix vaccine. © (Riordan Clinic) 2004 - 2017 For many, the worst consequences are the symptoms of cataplexy. People generally think of fats as a bad thing to have in their diet, but some fats, including squalene, are very healthy for you. U.S. Department of Defense (DoD) officials considered anthrax to be a likely organism that could be weaponized and a licensed anthrax vaccine had been stockpiled for emergency use since 1987.3 Military personnel from the United Kingdom also were given vaccines for anthrax, the plague and pertussis and Canadian military personnel re… Long List of Side Effects Referring to squalene in her extensive article on adjuvants, Dr. Scheibner writes, “This adjuvant contributed to the cascade of reactions called “Gulf War syndrome”, documented in the soldiers involved in the Gulf War. "The absolutely worst thing that could happen," commented Richard Bergstr�m, the Director - General of the European Federation of Pharmaceutical Industries and Associations, EFPIA. http://www.medterms.com/script/main/art.asp?articlekey=99584, On 11 June 2009, the World Health Organization (WHO) declared that the swine flu had developed into a full scale world epidemic - a pandemic alert to Phase 6. Animal and plant squalene is too unstable to be used in skin care products. Squalene (with an “e”) has been shown in scientific research to decrease skin damage by UV radiation, LDL levels and cholesterol in the blood, prevent cardiovascular diseases and has anti-tumor and anticancer effects against ovarian, breast, lung and colon cancer. According to the authorities, much research is still underway concerning the details of the vaccine injury. However, OMNS is unable to respond to individual emails. Squalene must be hydrogenated to be included in skin care products. Oral capsules are readily available in Asian health food stores and the substance is also widely used in cosmetics. Finally, the contract protected GSK from any claim for financial compensation in case the delivered vaccine would have any side effects. The symptoms they developed included arthritis, fibromyalgia, …